hydrocodone-pseudoephedrine (generic name)

Tussgen (brand name)

It is used to treat the cough and congestion of colds or respiratory infections
(hye droe KOE done; soo doe e FED rin)
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What is this medicine?

HYDROCODONE; PSEUDOEPHEDRINE (hye droe KOE done; soo doe e FED rin) is a combination of a cough suppressant with a decongestant. It is used to treat the cough and congestion of colds or respiratory infections.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • diarrhea
  • drug abuse or addiction
  • glaucoma
  • head trauma
  • heart disease
  • high blood pressure
  • if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • lung or breathing disease, like asthma
  • stomach or intestinal problems
  • trouble passing urine
  • an unusual or allergic reaction to codeine, hydrocodone, pseudoephedrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction to this medicine.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol
  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • atropine
  • antihistamines for allergy, cough and cold
  • barbiturates like phenobarbital
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • ipratropium
  • medicines for chest pain, heart disease, high blood pressure, or heart rhythm problems
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • muscle relaxants
  • naltrexone
  • narcotic medicines (opiates) for pain
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • tramadol

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Last Updated: August 27, 2012
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