hydrochlorothiazide-triamterene (generic name)

It helps you make more urine and lose the extra water from your body
(hye droe klor oh THYE a zide; trye AM ter een)
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What is this medicine?

HYDROCHLOROTHIAZIDE; TRIAMTERENE (hye droe klor oh THYE a zide; trye AM ter een) is a diuretic. It helps you make more urine and lose the extra water from your body. This medicine is used to treat high blood pressure and edema or swelling from excess water.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • immune system problems, like lupus
  • kidney disease or stones
  • liver disease
  • small amount of urine or difficulty passing urine
  • an unusual or allergic reaction to triamterene, hydrochlorothiazide, sulfa drugs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on your prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

Remember that you will need to pass urine frequently after taking this medicine. Do not take your doses at a time of day that will cause you problems. Do not take at bedtime.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • eplerenone

This medicine may also interact with the following medications:

  • cyclosporine
  • heart medicines like ACE inhibitors, digoxin, dofetilide, eplerenone, angiotensin II antagonists, and medicines for blood pressure
  • lithium
  • medicines for diabetes
  • medicines for inflammation like indomethacin
  • medicines that relax muscles for surgery
  • other diuretics
  • potassium
  • sotalol
  • tacrolimus

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular check ups. You will need lab work done before you start this medicine and regularly while you are taking it. Check your blood pressure regularly. Ask your health care professional what your blood pressure should be, and when you should contact them. If you are a diabetic, check your blood sugar as directed. Do not stop taking your medicine unless your doctor tells you to.

You may need to be on a special diet while taking this medicine. Ask your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid or limit alcoholic drinks.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

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Last Updated: September 07, 2011
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