histrelin (generic name)
Supprelin (brand name)
It is used to treat the symptoms of advanced prostate cancer
(his TREL in)
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What is this medicine?HISTRELIN (his TREL in) is used to treat the symptoms of advanced prostate cancer. The implant contains a drug that is like a natural hormone in the body called gonadotropin-releasing hormone (GnRH). It is placed under the skin and releases the drug over 12 months.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
How should I use this medicine?This medicine is placed under the skin of your arm by a health care professional in a clinic or office. After the implant is placed, keep the insertion site clean and dry for 24 hours. Avoid heavy lifting and strenuous exercise for 7 days after implant insertion. The surgical strips over the site should be allowed to fall off on their own over several days. The implant must be removed after 12 months. At this time, a new implant may be inserted to continue therapy.
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.
What if I miss a dose?This does not apply. After 1 year, the implant will have to be removed. If you need to continue this medicine, the implant will be replaced at that time.
What may interact with this medicine?
What should I watch for while using this medicine?Visit your doctor or health care professional for regular checks on your progress. During the first week, your symptoms may get worse but then will start to get better as you continue your treatment. You may get hot flashes, increased bone pain, increased difficulty passing urine, or an aggravation of nerve symptoms. Discuss these effects with your doctor or health care professional. Some of these may get better with continued use of this medicine.
Rarely, the implant can be expelled from the body through the original incision site. It is possible that you may see the implant being expelled, or rarely, the implant may be expelled without you noticing it. If you believe the implant has been expelled from your body, call your doctor.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
Where should I keep my medicine?This drug is given in a hospital or clinic and will not be stored at home.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.