ethinyl estradiol-etonogestrel (generic name)

This medicine combines two types of female hormones, an estrogen and a progestin
(ETH in il es tra DYE ole; et oh noe JES trel)
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What is this medicine?

ETHINYL ESTRADIOL; ETONOGESTREL (ETH in il es tra DYE ole; et oh noe JES trel) vaginal ring is a flexible, vaginal ring used as a contraceptive (birth control method). This medicine combines two types of female hormones, an estrogen and a progestin. This ring is used to prevent ovulation and pregnancy. Each ring is effective for one month.

What should I tell my health care provider before I take this medicine?

They need to know if you have or ever had any of these conditions:
  • abnormal vaginal bleeding
  • blood vessel disease or blood clots
  • breast, cervical, endometrial, ovarian, liver, or uterine cancer
  • diabetes
  • gallbladder disease
  • heart disease or recent heart attack
  • high blood pressure
  • high cholesterol
  • kidney disease
  • liver disease
  • migraine headaches
  • stroke
  • systemic lupus erythematosus (SLE)
  • tobacco smoker
  • an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Insert the ring into your vagina as directed. Follow the directions on the prescription label. The ring will remain place for 3 weeks and is then removed for a 1-week break. A new ring is inserted 1 week after the last ring was removed, on the same day of the week. Do not use more often than directed.

A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.

Contact your pediatrician regarding the use of this medicine in children. Special care may be needed. This medicine has been used in female children who have started having menstrual periods.

What if I miss a dose?

You will need to replace your vaginal ring once a month as directed. If the ring should slip out, or if you leave it in longer or shorter than you should, contact your health care professional for advice.

What may interact with this medicine?

  • acetaminophen
  • antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin, and possibly penicillins or tetracyclines
  • aprepitant
  • ascorbic acid (vitamin C)
  • atorvastatin
  • barbiturate medicines, such as phenobarbital
  • bosentan
  • carbamazepine
  • caffeine
  • clofibrate
  • cyclosporine
  • dantrolene
  • doxercalciferol
  • felbamate
  • grapefruit juice
  • hydrocortisone
  • medicines for anxiety or sleeping problems, such as diazepam or temazepam
  • medicines for diabetes, including pioglitazone
  • modafinil
  • mycophenolate
  • nefazodone
  • oxcarbazepine
  • phenytoin
  • prednisolone
  • ritonavir or other medicines for HIV infection or AIDS
  • rosuvastatin
  • selegiline
  • soy isoflavones supplements
  • St. John's wort
  • tamoxifen or raloxifene
  • theophylline
  • thyroid hormones
  • topiramate
  • warfarin

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Last Updated: December 03, 2009
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