esmolol (generic name)

Brevibloc (brand name)

Beta-blockers reduce the workload on the heart and help it to beat more regularly
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What is this medicine?

ESMOLOL is a beta-blocker. Beta-blockers reduce the workload on the heart and help it to beat more regularly. This medicine is used to slow down a fast heart rate and reduce high blood pressure.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • heart or vessel disease like slow heart rate, worsening heart failure, heart block, sick sinus syndrome or Raynaud's disease
  • kidney disease
  • low blood pressure
  • lung or breathing disease, like asthma or emphysema
  • pheochromocytoma
  • an unusual or allergic reaction to esmolol, other beta-blockers, medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection or infusion into a vein. It is usually given by a health-care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • sotalol

This medicine may also interact with the following medications:

  • digoxin
  • medicines for high blood pressure
  • morphine
  • reserpine
  • succinylcholine
  • warfarin

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • cold, tingling, or numb hands or feet
  • confusion
  • decreased blood pressure
  • difficulty breathing, wheezing
  • dizziness or fainting spells
  • pain, swelling, redness or irritation at the injection site
  • slow heart rate (less than 50 beats per minute)
  • sweating
  • swollen legs and ankles
  • vomiting

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • headache
  • nausea
  • unusual tiredness

Where should I keep my medicine?

This does not apply. You will not be given this medicine to store at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: April 20, 2009
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