eptifibatide (generic name)

Integrilin (brand name)

It prevents your blood from clotting during episodes of chest pain or a heart attack
(ep TIF i ba tide)
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What is this medicine?

EPTIFIBATIDE (ep TIF i ba tide) prevents your blood from clotting during episodes of chest pain or a heart attack. This medicine may also be used to prevent blood clots during a procedure to treat a blocked heart artery.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • bleeding such as vomiting blood, black or red stools, or pink or red urine within the past 30 days
  • high blood pressure
  • injury or surgery within the past 6 weeks
  • kidney disease
  • previous stroke
  • took a drug to prevent blood clots like warfarin in the past week
  • an unusual or allergic reaction to eptifibatide, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

  • aspirin and aspirin-like medicines
  • clopidogrel
  • dipyridamole
  • herbal products containing feverfew, garlic, ginger, ginkgo, or horse chestnut
  • medicines that break up blood clots like alteplase, reteplase, streptokinase, and urokinase
  • medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • ticlopidine

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • back pain
  • black, tarry stools
  • blood in the urine
  • breathing problems
  • coughing up blood
  • feeling faint or lightheaded, falls
  • pinpoint red spots on the skin
  • unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • pain at site where injected

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Last Updated: April 21, 2009
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