dronedarone (generic name)

Multaq (brand name)

It helps make your heart beat regularly
(droe NE da rone)
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What is this medicine?

DRONEDARONE (droe NE da rone) is an antiarrhythmic drug. It helps make your heart beat regularly.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • heart failure
  • history of irregular heartbeat
  • liver disease
  • liver or lung problems with the past use of amiodarone
  • low levels of magnesium in the blood
  • low levels of potassium in the blood
  • other heart disease
  • an unusual or allergic reaction to dronedarone, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take one tablet with the morning meal and one tablet with the evening meal. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take thi medicine with any of the following medications:
  • arsenic trioxide
  • certain antibiotics like clarithromycin, erythromycin, telithromycin
  • cyclosporine
  • droperidol
  • haloperidol
  • medicines for depression called tricyclic antidepressants
  • medicines for fungal infections like itraconazole, ketoconazole, voriconazole
  • medicines for malaria like chloroquine and halofantrine
  • medicines to control heart rhythm like amiodarone, disopyramide, dofetilide, flecainide, ibutilide, quinidine, propafenone, sotalol
  • methadone
  • pentamidine
  • pimozide
  • nefazodone
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • ritonavir
  • troleandomycin
  • ziprasidone

This medicine may also interact with the following medications:

  • beta-blockers like metoprolol and propranolol
  • calcium channel blockers like diltiazem and verapamil
  • digoxin
  • grapefruit juice
  • medicines for cholesterol like atorvastatin, lovastatin, simvastatin
  • medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • rifampin
  • sirolimus
  • St. John's Wort
  • tacrolimus

What should I watch for while using this medicine?

Your condition will be monitored closely when you first begin therapy. Often, this drug is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your doctor or health care professional for regular checks on your progress. Because your condition and use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and doctor or health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

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Last Updated: June 18, 2013
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