Codeine Sulfate (generic name)

It is used to treat mild to moderate pain
(KOE deen)
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What is this medicine?

CODEINE (KOE deen) is a pain reliever. It is used to treat mild to moderate pain.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • brain tumor
  • drug abuse or addiction
  • head injury
  • heart disease
  • frequently drink alcohol containing drinks
  • kidney disease or problems going to the bathroom
  • liver disease
  • lung disease, asthma, or breathing problems
  • an unusual or allergic reaction to codeine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you've taken too much of this medicine contact a poison control center or emergency room at once.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

  • alcohol
  • antihistamines for allergy, cough and cold
  • antiviral medicines used for HIV or AIDS
  • atropine
  • certain antibiotics like erythromycin and clarithromycin
  • certain medicines for bladder problems like oxybutynin, tolterodine
  • certain medicines for depression, anxiety, or psychotic disturbances
  • certain medicines for fungal infections like ketoconazole and itraconazole
  • certain medicines for irregular heart beat like amiodarone, propafenone, quinidine
  • certain medicines for Parkinson's disease like benztropine, trihexyphenidyl
  • certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
  • certain medicines for sleep
  • certain medicines for stomach problems like dicyclomine, hyoscyamine
  • certain medicines for travel sickness like scopolamine
  • certain medicines used for nausea like dronabinol, droperidol, nabilone
  • ipratropium
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for anesthesia
  • muscle relaxants
  • naltrexone
  • narcotic medicines (opiates) for pain
  • phenobarbital
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
  • rifampin
  • tramadol

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Last Updated: September 14, 2012
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