choline salicylate-magnesium salicylate (generic name)

Trilisate (brand name)

It is used to treat arthritis in children and adults
(KOE leen sa LI sa late; mag NEE zhum sa LI sa late)
Table of Contents
powered by healthline

Average Ratings

What is this medicine?

CHOLINE SALICYLATE; MAGNESIUM SALICYLATE (KOE leen sa LI sa late; mag NEE zhum sa LI sa late) is an anti-inflammatory pain reliever related to aspirin. It is used to treat arthritis in children and adults. It is also used to treat mild to moderate pain and fever.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma
  • drink more than 3 alcohol-containing drinks a day
  • gout
  • kidney disease
  • liver disease
  • stomach bleeding or ulcers
  • an unusual or allergic reaction to choline salicylate, magnesium salicylate, other salicylates, aspirin, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the prescription label. You can mix this medicine with fruit juice or water just before taking it. Use a specially marked spoon or container to measure this medicine. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take this medicine with food if it upsets your stomach. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • ketorolac
  • medicines that treat or prevent blood clots like warfarin
  • methotrexate
  • probenecid

This medicine may also interact with the following medications:

  • acetazolamide
  • alcohol
  • aspirin and aspirin-like drugs
  • medicines for diabetes
  • medicines for gout
  • methazolamide
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • phenytoin
  • steroid medicines like prednisone or cortisone
  • sulfinpyrazone
  • valproic acid

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Do not take medicines such as ibuprofen and naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.

This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. Ulcers and bleeding can happen without warning symptoms and can cause death. To reduce your risk, do not smoke cigarettes or drink alcohol while you are taking this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Page: 1 2 Next >
Last Updated: March 23, 2009
Licensed from
Top of page
General Drug Tools
General Drug Tools view all tools
Tools for
Healthy Living
Tools for Healthy Living view all tools
Search Tools
Search Tools view all tools
Insurance Plan Tools
Insurance Plan Tools view all tools

What is a reference number?

When you register on this site, you are assigned a reference number. This number contains your profile information and helps UnitedHealthcare identify you when you come back to the site.

If you searched for a plan on this site in a previous session, you might already have a reference number. This number will contain any information you saved about plans and prescription drugs. To use that reference number, click on the "Change or view saved information" link below.

You can retrieve information from previous visits to this site, such as saved drug lists and Plan Selector information.