chlorpheniramine/dextromethorp/phenylephrine (generic name)

Corfen-DM (brand name)

It is used to treat the symptoms of allergies and the common cold
(klor fen IR a meen; dex troe meth OR fan; fen il EF rin)
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What is this medicine?

CHLORPHENIRAMINE; DEXTROMETHORPHAN; PHENYLEPHRINE (klor fen IR a meen; dex troe meth OR fan; fen il EF rin) is a combination of an antihistamine, a cough suppressant, and a decongestant. It is used to treat the symptoms of allergies and the common cold. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • eczema
  • glaucoma
  • heart disease
  • high blood pressure
  • lung or breathing disease, like asthma
  • phenylketonuria
  • stomach ulcer
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • thyroid disease
  • trouble passing urine
  • an unusual or allergic reaction to chlorpheniramine; dextromethorphan; phenylephrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth. Follow the directions on the label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply. Do not give this medicine to children under 2 years old.

Patients over 60 years old may have a stronger reaction to this medicine and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for cold, cough, or allergy
  • medicines for weight loss
  • procarbazine
  • some medicines for migraine headaches
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • alcohol
  • barbiturates like phenobarbital
  • mecamylamine
  • medicines for chest pain, heart disease, high blood pressure or heart rhythm problems
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • reserpine
  • some herbal or nutritional supplements
  • some medicines for Parkinson's disease
  • some medicines for pain

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. If you have a fever, skin rash, or persistent headache, see your doctor. Do not take this medicine for more than one week unless directed by your doctor. Do not take more than the recommended dose.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not stand or sit up quickly, especially if you are an older patient. Alcohol may increase dizziness and drowsiness. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

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Last Updated: March 31, 2009
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