atropine/hyoscyamine/PB/scopolamine (generic name)

Hyosophen (brand name)

It is used to treat different bowel problems including irritable bowel syndrome, acute enterocolitis, or duodenal ulcer.
(A troe peen; hye oh SYE a meen; fee noe BAR bi tal; skoe POL a meen)
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What is this medicine?

ATROPINE; HYOSCYAMINE; PHENOBARBITAL; SCOPOLAMINE (A troe peen; hye oh SYE a meen; fee noe BAR bi tal; skoe POL a meen) is used to treat different bowel problems including irritable bowel syndrome, acute enterocolitis, or duodenal ulcer.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • an alcohol or drug abuse problem
  • constipation
  • diarrhea
  • glaucoma
  • heart disease
  • hiatal hernia and esophageal reflux or GERD
  • kidney disease
  • liver disease
  • myasthenia gravis
  • porphyria
  • prostate trouble
  • stomach problems
  • ulcerative colitis
  • an unusual or allergic reaction to atropine; hyoscyamine; phenobarbital; scopolamine, other medicines, lactose, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label.

Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • voriconazole

This medicine may also interact with the following medications:

  • alcohol
  • cyclosporine
  • female hormones, like estrogens or progestins and birth control pills
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • medicines for HIV infection like indinavir, nelfinavir, ritonavir, and saquinavir
  • warfarin

What should I watch for while using this medicine?

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

Avoid extreme heat (e.g., hot tubs, saunas). This medication can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • fast heartbeat or palpitations
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • unusual bleeding or bruising
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • anxiety or nervousness
  • constipation
  • dizziness or fainting spells
  • drowsiness
  • dry mouth
  • headache
  • nausea or vomiting

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Last Updated: March 11, 2009
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