amiodarone (generic name)

Pacerone (brand name)

It helps make your heart beat regularly
(a MEE oh da rone)
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What is this medicine?

AMIODARONE (a MEE oh da rone) is an antiarrhythmic drug. It helps make your heart beat regularly. Because of the side effects caused by this medicine, it is only used when other medicines have not worked. It is usually used for heartbeat problems that may be life threatening.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • liver disease
  • lung disease
  • other heart problems
  • thyroid disease
  • an unusual or allergic reaction to amiodarone, iodine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. However, you should always take it the same way each time. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • abarelix
  • amoxapine
  • apomorphine
  • arsenic trioxide
  • certain macrolide antibiotics
  • certain quinolone antibiotics
  • cisapride
  • droperidol
  • haloperidol
  • hawthorn
  • levomethadyl
  • maprotiline
  • medicines for malaria like chloroquine and halofantrine
  • medicines for mental depression such as tricyclic antidepressants
  • medicines to control heart rhythm like disopyramide, dofetilide, ibutilide, propafenone, and sotalol
  • methadone
  • mibefradil
  • pentamidine
  • phenothiazines like chlorpromazine, mesoridazine, and thioridazine
  • pimozide
  • probucol
  • ranolazine
  • sertindole
  • vardenafil
  • red yeast rice
  • ziprasidone

This medicine may also interact with the following medications:

  • beta blockers
  • calcium channel blockers
  • cholestyramine
  • cimetidine
  • clopidogrel
  • cyclosporine
  • dextromethorphan
  • digoxin
  • diuretics
  • fentanyl
  • flecainide
  • fluindione
  • general anesthetics
  • grapefruit juice
  • lidocaine
  • loratadine
  • medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
  • medicines for HIV, AIDS
  • medicines for seizures such as phenytoin
  • medicines for thyroid problems
  • medicines to lower cholesterol such as atorvastatin, cerivastatin, lovastatin, or simvastatin
  • methotrexate
  • procainamide
  • quinidine
  • rifampin, rifabutin, or rifapentine
  • St. John's Wort
  • trazodone
  • warfarin

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Last Updated: July 16, 2010
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