ambrisentan (generic name)
Letairis (brand name)
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What is this medicine?AMBRISENTAN (am bri SEN tan) is used to treat pulmonary hypertension. This medicine may help make exercise and breathing easier.
What should I tell my health care provider before I take this medicine?They need to know if you have any of these conditions:
- scarring or thickening of the lungs
- liver disease
- an unusual or allergic reaction to ambrisentan, other medicines, foods, dyes, or preservatives
- pregnant or trying to get pregnant
How should I use this medicine?Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What if I miss a dose?If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
What should I watch for while using this medicine?Visit your doctor for regular check ups. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.
This medicine can cause birth defects. Do not get pregnant while taking this drug. Females with child-bearing potential will need to have a negative pregnancy test before starting this medicine and every month while taking this medicine. Use 2 reliable forms of birth control together while you are taking this medicine and for 1 month after you stop taking this medicine. If you think that you might be pregnant talk to your doctor right away.
Because of the risks of birth defects, this medicine is available only through a special program. Doctors, pharmacies, and patients must meet all of the conditions of the program. Your health care provider will help you get signed up with the program if you need this medicine.
What side effects may I notice from receiving this medicine?Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- dark urine
- fast, irregular heartbeat
- feeling faint or lightheaded, falls
- general ill feeling or flu-like symptoms
- light-colored stools
- loss of appetite, nausea
- right upper belly pain
- sudden weight gain
- swelling of the ankles or legs
- unusually weak or tired
- yellowing of eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
- congested or runny nose
- flushing of the skin
- sore throat
- stomach upset
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.