acetaZOLAMIDE (generic name)

It is used to treat glaucoma and some seizure disorders
(a set a ZOLE a mide)
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What is this medicine?

ACETAZOLAMIDE (a set a ZOLE a mide) is used to treat glaucoma and some seizure disorders. It may be used to treat edema or swelling from heart failure or from other medicines.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • adrenal gland disease
  • closed-angle glaucoma
  • kidney disease
  • liver disease
  • low levels of sodium or potassium in the blood
  • an unusual or allergic reaction to acetazolamide, sulfa drugs, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is usually given by a health care professional in a hospital or clinic setting.

If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.

It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • methazolamide

This medicine may also interact with the following medications:

  • aspirin and aspirin-like medicines
  • cyclosporine
  • lithium
  • medicine for diabetes
  • methenamine
  • other diuretics
  • phenytoin
  • primidone
  • quinidine
  • sodium bicarbonate
  • stimulant medicines like dextroamphetamine

What should I watch for while using this medicine?

Visit your doctor for regular check ups. You will need blood work done regularly. If you are diabetic, check your blood sugar as directed.

You may need to be on a special diet while taking this medicine. Ask your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • black tarry stools
  • breathing problems
  • confusion, depression
  • dark urine
  • fever
  • numbness, tingling in feet or hands
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • ringing in the ears
  • seizures
  • unusually weak or tired
  • yellowing of eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • change in taste
  • diarrhea
  • headache
  • loss of appetite
  • nausea, vomiting
  • passing urine more often

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Last Updated: March 11, 2009
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