acetaminophen-phenyltoloxamine (generic name)

Uni-Perr (brand name)

It is used to treat the symptoms of allergies
(a set a MEE noe fen; fen ill toe LOX a meen)
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What is this medicine?

ACETAMINOPHEN; PHENYLTOLOXAMINE (a set a MEE noe fen; fen ill toe LOX a meen) is a combination of a pain reliever and an antihistamine. It is used to treat the symptoms of allergies. It may help with headache, runny nose, and sneezing. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • glaucoma
  • if you frequently drink alcohol containing drinks
  • kidney disease
  • liver disease
  • lung or breathing disease, like asthma
  • trouble passing urine
  • an unusual or allergic reaction to acetaminophen, phenyltoloxamine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. If it upsets your stomach, take it with food or milk. Tablets may be broken in half. Do not chew or crush this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While some forms of this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol

This medicine may also interact with the following medications:

  • acetaminophen
  • barbiturates, like phenobarbital
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • muscle relaxers
  • narcotic pain medicines
  • other medicines for cold, cough or allergy
  • phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • fever, sore throat
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • unusually weak or tired
  • yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • drowsiness
  • dry eyes, mouth
  • loss of appetite
  • stomach upset

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Last Updated: November 24, 2010
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