Varicose Veins supplements
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Rutin is a yellow crystalline flavonol glycoside (C 27 H 30 O 16 ) that occurs in various plants (rue, tobacco, buckwheat, etc.). Upon hydrolysis (a chemical reaction that uses water to break down a compound), rutin yields quercetin and rutinose. Rutin is used in many countries as a vasoprotectant and is an ingredient in numerous multivitamin preparations and herbal remedies. The rutosides are naturally occurring flavonoids that have documented effects on capillary permeability and edema (swelling) and have been used for the treatment of disorders of the venous and microcirculatory systems. There is some evidence for the use of rutin for chronic venous insufficiency, edema, hemorrhoids, microangiopathy (disease of small blood vessels), varicosis and venous disorders. Well presented clinical trials are required in these fields before solid recommendations can be made. Formulations, mainly consisting of the trihydroxyethyl derivative of rutin, are used in Europe, Mexico and other Latin American countries for the treatment of such venous disorders as varicose veins and hemorrhoids. The generic name for these formulations is troxerutin. Troxerutin has been widely used in Europe since the mid-1960s.
Gotu kola is from the perennial creeping plant, Centella asiatica (formerly known as Hydrocotyle asiatica ) , which is a member of the parsley family. It is native to India, Madagascar, Sri Lanka, Africa, Australia, China, and Indonesia. Gotu kola has a long history of use, dating back to ancient Chinese and Ayurvedic medicine. Gotu kola is mentioned in the Shennong Herbal , compiled in China roughly 2,000 years ago, and has been widely used medicinally since 1700 AD. It has been used to treat leprosy in Mauritius since 1852; to treat wounds and gonorrhea in the Philippines; and to treat fever and respiratory infections in China. The most popular use of gotu kola in the United States is the treatment for varicose veins or cellulitis. Preliminary evidence suggests short-term efficacy (6-12 months) of the total triterpenic fraction of Centella asiatica (TTFCA) in the treatment of "chronic venous insufficiency" (a syndrome characterized by lower extremity swelling, varicosities, pain, itching, atrophic skin changes, and ulcerations, possibly due to venous valvular incompetence or a post-thrombotic syndrome). While quality human evidence on the efficacy of gotu kola is still lacking, gotu kola can now be found worldwide as a component of skin creams, lotions, hair conditioners, shampoos, tablets, drops, ointments, powders, and injections. Gotu kola is not related to the kola nut ( Cola nitida , Cola acuminata ). Gotu kola is not a stimulant and does not contain caffeine.
Bilberry, a close relative of blueberry, has a long history of medicinal use. The dried fruit has been popular for the symptomatic treatment of diarrhea, for topical relief of minor mucus membrane inflammation, and for a variety of eye disorders, including poor night vision, eyestrain, and myopia. Bilberry fruit and its extracts contain a number of biologically active components, including a class of compounds called anthocyanosides. These have been the focus of recent research in Europe. Bilberry extract has been evaluated for efficacy as an antioxidant, mucostimulant, hypoglycemic, anti-inflammatory, "vasoprotectant," and lipid-lowering agent. Although pre-clinical studies have been promising, human data are limited and largely of poor quality. At this time, there is not sufficient evidence in support of (or against) the use of bilberry for most indications. Notably, the evidence suggests a lack of benefit of bilberry for the improvement of night vision. Bilberry is commonly used to make jams, pies, cobblers, syrups, and alcoholic/non-alcoholic beverages. Fruit extracts are used as a coloring agent in wines.