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Syphilis is a sexually transmitted infection caused by a type of bacteria known as Treponema pallidum. The second stage of syphilis is marked by a non-itchy rash on the palms and soles.
Drug abuses occurs when you are not able to control your use of prescribed drugs or are using an illegal substance to the point that it interferes with your ability to function.
Drinking too much alcohol, or being unable to control consumption, can indicate alcohol abuse or alcoholism. Too much alcohol in the blood or having withdrawal can lead to serious mental and physical symptoms.