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Thyme has been used medicinally for thousands of years. Beyond its common culinary application, it has been recommended for a myriad of indications, based upon proposed antimicrobial, antitussive, spasmolytic and antioxidant activity. To date, there are no well-defined controlled clinical trials to support thyme monotherapy for use in humans. Thymol, one of the constituents of thyme, is contained in antiseptic mouthwashes, with limited clinical studies in the available literature to verify its efficacy as a monotherapy in dental outcomes, such as reductions in plaque formation, gingivitis and caries. Traditional uses of thyme include for coughs and upper respiratory congestion; it continues to be one of the most commonly recommended herbs in Europe for these indications. The German Commission E (expert panel), has approved thyme for symptoms of bronchitis, whooping cough, and catarrh (inflammation of upper respiratory tract mucous membranes). Experts have recommended the use of thymol in treatment of actinomycosis (lumpy jaw disease), onycholysis (separation or loosening of a fingernail or toenail from its nail bed), and paronychia (inflammation of the tissue surrounding a fingernail or toenail) due to its antifungal properties..
Cordyceps sinensis , the Cordyceps species most widely used as a dietary supplement, naturally grows on the back of the larvae of a caterpillar from the moth Hepialus armoricanus Oberthur found mainly in China, Nepal, and Tibet. The mycelium invades the caterpillar and eventually replaces the host tissue. The stroma (fungal fruit body) grows out of the top of the caterpillar. The remaining structures of the caterpillar along with the fungus are dried and sold as the dietary supplement cordyceps. Commonly known as "dong chong xia cao" (summer-plant, winter-worm) in Chinese, cordyceps has been used as a tonic food in China and Tibet and has been used as a food supplement and tonic beverage among the rich because of its short supply due to over harvesting. It is also an ingredient in soups and other foods used traditionally in Chinese medicine for thousands of years helping debilitated patients recover from illness. Cordyceps is used therapeutically for asthma, bronchitis, chemoprotection, exercise performance, hepatitis B, hepatic cirrhosis, hyperlipidemia (high cholesterol), as an immunosuppressive agent, and in chronic renal failure. The fungus became popular in 1993 when two female Chinese athletes, who admitted using cordyceps supplements, beat the world records in the track and field competition at the Stuttgart World Championships for the 1,500-, 3,000-, and 10,000-meter runs. The women were drug tested for any banned substances such as steroids and were negative. Their coach attributed the performance to the cordyceps supplementation.
Evening primrose oil (EPO) contains an omega-6 essential fatty acid, gamma-linolenic acid (GLA), which is believed to be the active ingredient. EPO has been studied in a wide variety of disorders, particularly those affected by metabolic products of essential fatty acids. However, high-quality evidence for its use in most conditions is still lacking.